At the end of the course the participants will be able to set up designs for formulations and to analyse the experimental results.
INTENDED AUDIENCE & PRIOR KNOWLEDGE
Participants in this course are expected to have completed DOE-I. The target audience is equal to those for DOE-I: R&D in chemistry, chemical and biological pharmacy, plastics processing, paint industry.
- Formulations – an introduction
- Designs for regular design regions
- Scheffé models
- Analysis, interpretation and visualisation of mixture models
- Designs for irregular design regions (optimal designs)
- Irregular regions: Response Surface Modelling
- Mixture-process problems
CASES & APPLICATIONS
- To arrive at a recipe for paint that is easy to apply, has sufficient coverage, hardens quickly and is UV resistant.
- Choose the composition of a tablet so that it remains whole in its packaging, passes the stomach, but then easily disintegrates.
- Make a blend of those types of polymer, each with a dozen candidates, to make a plastic with the right impact strength, flexibility and being coatable.
- Optimizing a process for reactive extrusion, where the polymer blend as well as the reagent and the extruder settings must be selected.